منابع مشابه
The identification of Hoxc8 target genes.
Hox genes encode transcription factors that control spatial patterning during embryogenesis. To date, downstream targets of Hox genes have proven difficult to identify. Here, we describe studies designed to identify target genes under the control of the murine transcription factor Hoxc8. We used a mouse 16,463 gene oligonucleotide microarray to identify mRNAs whose expression was altered by the...
متن کاملGenes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes
The subnetwork of Hoxc8 and its neighboring genes. The genes coexpressed with Hoxc8 were analyzed using the Ingenuity Pathway Analysis tool. Hoxc8 is a node of the subnetwork comprising Fzd2, Adam19, Ly6a, Pmp22, Serpinf1, and Pbx1. The collagen family genes are the neighboring genes
متن کاملErratum to: Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes
Identifying Hoxc8 target genes is at the crux of understanding the Hoxc8-mediated regulatory networks underlying its roles during development. However, identification of these genes remains difficult due to intrinsic factors of Hoxc8, such as low DNA binding specificity, context-dependent regulation, and unknown cofactors. Therefore, as an alternative, the present study attempted to test whethe...
متن کاملthe impact of skopos on syntactic features of the target text
the present study is an experimental case study which investigates the impacts, if any, of skopos on syntactic features of the target text. two test groups each consisting of 10 ma students translated a set of sentences selected from advertising texts in the operative and informative mode. the resulting target texts were then statistically analyzed in terms of the number of words, phrases, si...
15 صفحه اولIdentification of Set1 Target Genes
The Set1 complex, a histone methyltransferase complex found in S. cerevisiae (budding yeast), is the only histone methyltransferase responsible for catalyzing methylation of histone H3 at Lysine 4. It possesses homologues in other species, humans included. While yeast only have the Set1 complex, the human homologues of the yeast Set1 complex include mixed-lineage leukemia family (MLL1-4), Set1 ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2005
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0409700102